1998

Hydroxyurea

Is the first drug approved to treat sickle cell disease in adults

20+ YEARS

2017

L-glutamine (Endari)

Approved to treat sickle cell disease in adults and children

Hydroxyurea (Siklos)

Approved to treat sickle cell disease in children

2019

Crizanlizumab (Adakveo)

Approved to treat pain crises in adults and pediatric patients 16 years and older

Voxelotor (Oxbryta)

Approved to help prevent sickling in patients 12 years and older

There’s more Hope on the Horizon!

Watch the video to learn more about clinical studies.

Clinical studies are looking for participants so that they can conduct the research necessary to improve understanding about potential treatments.

number of phase 01 sickle cell studies currently recruiting

number of phase 02 sickle cell studies currently recruiting

number of phase 03 sickle cell studies currently recruiting

Information per clinicaltrials.gov, 5/4/22. Visit clinicaltrials.gov to learn more about recruitment and participation in clinical trials.

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ClinicalTrials.gov is a database of privately and publicly funded clinical studies conducted around the world. Explore 259,383 research studies in all 50 states and in 201 countries.

ClinicalTrials.gov is a resource provided by the U.S. National Library of Medicine.

The National Institutes of Health (NIH), a part of the U.S. Department of Health and Human Services, is the nation’s medical research agency — making important discoveries that improve health and save lives.

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The FDA's organization consists of the Office of the Commissioner and four directorates overseeing the core functions of the agency: Medical Products and Tobacco, Foods, Global Regulatory Operations and Policy, and Operations.

CDC laboratories routinely work with some of the most deadly germs in the world – identifying health threats and conducting vital public health research. CDC constantly develops and reviews extensive laboratory guidelines and procedures to protect both the public and laboratory workers.

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Our vision is a world without sickle cell disease

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